IL-6 and lipid metabolism
نویسندگان
چکیده
منابع مشابه
IL-6 and lipid metabolism
Interleukin-6 (IL-6) plays essential roles not only in the immune response, but also in hematopoiesis, and in the central nervous system. Dysregulated production of IL-6 has been found in chronic inflammatory autoimmune diseases such as rheumatoid arthritis (RA). Many reports have indicated that lipid levels, such as total cholesterol and triglyceride levels, are changed under inflammatory cond...
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Interleukin (IL)-6 is chronically elevated in type 2 diabetes but also during exercise. However, the exact metabolic role, and hence the physiological significance, has not been elucidated. The objective of this study was to investigate the in vivo effect of recombinant human (rh) IL-6 on human fat and glucose metabolism and signaling of both adipose tissue and skeletal muscle. Eight healthy po...
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Background: Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth-supporting tissues. Environmental and genetic factors as well as the immune system participate in this process. Recent studies have attempted to elucidate the role of cytokine networks involved in periodontal diseases. Objective: To assess and compare the levels of IL-4, IL-6 and IL-...
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By using a sandwich ELISA, soluble human IL-6 receptor (sIL-6 R) levels were measured in the sera of 20 healthy children and of 25 patients with systemic juvenile rheumatoid arthritis (JRA). In patients with systemic JRA, serum sIL-6 R levels (114.6 +/- 37.7 ng/ml) were significantly lower (P < 0.01) than those of healthy children (161.2 +/- 45.5 ng/ml). Serum sIL-6 R levels were negatively cor...
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ژورنال
عنوان ژورنال: Inflammation and Regeneration
سال: 2011
ISSN: 1880-8190,1880-9693
DOI: 10.2492/inflammregen.31.325